Blood Transfusion : Age of blood products

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More information on this topic is available see: Age of blood – background document

Patient group	Age of red blood cells on day of issue	Considerations
Neonatal exchange transfusion	< 5 days	Kell negative, CMV negative, Rh and phenotype matched
Intrauterine transfusion	< 5 days	Kell negative, CMV negative, Rh and phenotype matched
Paediatric large volume transfusion* Cardiac surgery requiring cardiopulmonary bypass ECLS Craniofacial surgery	< 7 days	In an emergency, the blood bank scientist will issue the most appropriate unit available at that time
Paediatric – routine transfusion Post-op surgical patient Oncology patients Solid organ transplantation	Standard issue
Massive transfusion	Aim < 10 days	In an emergency, the blood bank scientist will issue the most appropriate unit available at that time
Chronically transfused patients - Congenital anaemia who are transfusion dependent - Haemoglobinopathies (sickle cell disease, thalassaemia) - Aplastic anaemia	Aim < 14 days	Patients with haemoglobinopathies are matched for Rh and Kell. Extended phenotype matching for patients with alloantibodies. Extended phenotype matching may take precedence over age of red cells.
Small volume (top up) neonatal transfusions	Standard issue
Children and adolescents not included in any groups listed above	Standard issue